Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds Related Products (10723):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-117287

Deucravacitinib		99.93%
Deucravacitinib (BMS-986165) is a highly selective, orally bioavailable allosteric TYK2 inhibitor for the treatment of autoimmune diseases, which selectively binds to TYK2 pseudokinase (JH2) domain (IC₅₀=1.0 nM) and blocks receptor-mediated Tyk2 activation by stabilizing the regulatory JH2 domain. Deucravacitinib inhibits IL-12/23 and type I IFN pathways. Deucravacitinib, the FDA's world first de novo deuterium, is available for study in moderate to severe plaque psoriasis.

HY-N0390S1

L-Glutamine-¹³C₅		99.93%
L-Glutamine-¹³C₅ is the ¹³C-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells.

HY-13631AS

Exatecan-d₅ mesylate		99.83%
Exatecan-d₅ (DX8951f-d₅) mesylate is deuterium labeled Exatecan mesylate (HY-13631A). Exatecan mesylate is a DNA topoisomerase I inhibitor, with an IC₅₀ of 2.2 μM (0.975 μg/mL). Exatecan mesylate can be used in cancer research.

HY-Y0479S

L-Lactic acid-¹³C₃		99.9%
L-Lactic acid-¹³C₃ is a ¹³C-labeled L-Lactic acid (HY-Y0479). L-Lactic acid-¹³C₃ can be used for lactate metabolism research.

HY-Y0534S

Sodium cyanoboronhydride-d₃		99.85%
Sodium cyanoboronhydride-d₃ is the deuterium labeled Sodium cyanoboronhydride.

HY-181527S

N-(4-((3-Methoxy-4-(1-(methyl-d₃)-1H-1,2,4-triazol-3-yl)pyridin-2-yl)amino)-5-propionylpyridin-2-yl)cyclopropanecarboxamide		99.93%
N-(4-((3-Methoxy-4-(1-(methyl-d₃)-1H-1,2,4-triazol-3-yl)pyridin-2-yl)amino)-5-propionylpyridin-2-yl)cyclopropanecarboxamide is the deuterium labeled N-(4-((3-Methoxy-4-(1-(methyl)-1H-1,2,4-triazol-3-yl)pyridin-2-yl)amino)-5-propionylpyridin-2-yl)cyclopropanecarboxamide.

HY-15582S

Auristatin E-d₈		99.48%
Auristatin E-d₈ is the deuterium labeled Auristatin E (HY-15582). Auristatin E is a cytotoxic microtubule polymerization inhibitor with potent and selective antitumor activity. Auristatin E is a cytotoxin in antibody-drug conjugates (ADC). Auristatin E inhibits cell division by blocking the polymerisation of tubulin, promising for research in B-cell malignancies. Auristatin E, a synthetic analogue of the Dolastatin 10 (HY-15580), is linear peptides comprised of four amino acids.

HY-Y0721S1

3-Bromofluorobenzene-d₄		99.75%
3-Bromofluorobenzene-d₄ (m-Bromofluorobenzene-d₄) is the deuterium labeled 3-Bromofluorobenzene.

HY-108872S

Water-¹⁸O		99.99%
Water-¹⁸O is the ¹⁸O-labeled Water.

HY-N0390S8

L-Glutamine-¹⁵N₂		99.10%
L-Glutamine-¹⁵N₂ is the ¹⁵N-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells.

HY-B0617S

S-Adenosyl-L-methionine-d₃		99.70%
S-Adenosyl-L-methionine-d₃ (S-Adenosyl methionine-d₃) is the deuterated product of S-Adenosyl-L-methionine (HY-B0617). S-Adenosyl-L-methionine (S-Adenosyl methionine) is an orally active methyl group donor. S-Adenosyl-L-methionine is a dietary supplement with potent antidepressant effects. S-Adenosyl-L-methionine also has anti‑proliferative, pro‑apoptotic and anti‑metastatic roles in cancers. S-Adenosyl-L-methionine has the potential for, cancer, liver disease and osteoarthritis research.

HY-N0455AS6

L-Arginine-¹³C₆ hydrochloride		99.00%
L-Arginine-¹³C₆ (hydrochloride) is the ¹³C-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

HY-W013636S

2-Ketoglutaric acid-¹³C₅		99.92%
2-Ketoglutaric acid-¹³C₅ (Alpha-Ketoglutaric acid-¹³C₅) is a ¹³C labeled 2-Ketoglutaric acid (HY-W013636). 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC₅₀=15 mM).

HY-18569S

3-Indoleacetic acid-d₅		99.76%
3-Indoleacetic acid-d₅ is the deuterium labeled 3-Indoleacetic acid (HY-18569). 3-Indoleacetic acid-d₅ can be used as internal standard for assay of IAA releases by alkaline hydrolysis of ester and amide conjugates.

HY-N0390S

L-Glutamine-¹⁵N		99.6%
L-Glutamine-¹⁵N is the ¹⁵N-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells.

HY-Y0479AS

L-Lactic acid-¹³C₃ sodium (20% w/w in water)		99.91%
L-Lactic acid-¹³C₃ ((S)-2-hydroxypropanoic-¹³C₃) sodium (20% in water) is the ¹³C labeled L-Lactic acid. L-Lactic acid-¹³C₃ sodium (20% in water) can be used for lactate metabolism research.

HY-B1473AS

Serotonin-d₄		99.60%
Serotonin-d₄ is deuterium labeled Serotonin. Serotonin is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin is also a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM.

HY-N0623S2

L-Tryptophan-¹³C₁₁		99.78%
L-Tryptophan-¹³C₁₁ is the ¹³C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3.

HY-Y1269S

Ammonium chloride-¹⁵N		99.6%
Ammonium chloride-¹⁵N is the ¹⁵N labeled Ammonium chloride (HY-Y1269). Ammonium chloride, as a heteropolar compound with pH value regulation, can cause intracellular alkalization and metabolic acidosis thus effecting enzymatic activity and influencing the process of biological system. Ammonium chloride is an autophagy inhibitor. Ammonium chloride is also a lysosome inhibitor.

HY-N1428S1

Citric acid-¹³C₆		99.90%
Citric acid-¹³C₆ is the ¹³C-labeled Citric acid (HY-N1428). Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries.

Name
Email *

	Sorry, but the email address you supplied was invalid.